One of the most used tools for the identification and optimization of drug-treatment is therapeutic drug monitoring, applying the principles of clinical pharmacokinetics. The ultimate goal is to adapt the exposure of the drug to the proposed clinical objectives. For this, the student must know the different relationships between plasma concentration and pharmacological response, and the clinical pharmacokinetic principles.
Moreover, This unit will assess the main factors related to the patient that may affect drug therapy, as well as actions to optimize this treatment. So, it will assess the pathophysiologic condition of the patient, especially kidney and liver function as well as possible genetic polymorphisms that may affect treatment. Finally, the necessary changes in pharmacotherapy in special populations such as the elderly, pediatric patients, pregnant women, different races or gender will be studied.