Knowledge and skills for clinical evaluation, diagnosis, treatment, and monitoring of patients with HIV/AIDS and hepatitis. Knowledge and skills for clinical evaluation, diagnosis, treatment, and monitoring of patients infected with hepatitis B and C in coinfected and monoinfected cases.
|MASIA CANUTO, MARIA DEL MAR||■||■||■|
|BERNAL MORELL, ENRIQUE||■||■|
|ABRIL LÓPEZ DE MEDRANO, VICENTE||■||■|
|ORTEGA GONZÁLEZ, ENRIQUE||■||■|
|GALINDO PUERTO, MARÍA JOSÉ||■||■|
|USÓ BLASCO, JORDI||■||■|
|ALCAMI PERTEJO, JOSÉ||■||■|
|GARCÍA DELTORO, MIGUEL||■||■|
|LLENAS GARCIA, JARA||■||■|
|ESTRADA PEREZ, VICENTE||■||■|
|PADILLA URREA, SERGIO||■||■|
|GUTIERREZ RODERO, FELIX||■||■|
Competencies and learning outcomes
- Demonstrate systematic competence in the field of infectious diseases and mastery of research methods and skills related to infectious diseases.
- Be able to critically analyze, evaluate, and synthesize new and complex ideas in infectious diseases and international health.
- Know how to communicate with peers, the academic community as a whole, and society in general about infectious diseases and international health.
- Capability of promoting, within academic and professional contexts, technological, social, or cultural advancement in the field of infectious diseases and international health within a knowledge-based society.
- Demonstrate the ability to clinically use antibiotics (antibacterial, antifungal, antiparasitic, and antiviral) in order to design, plan, and implement programs for their management in different healthcare environments.
- Understand the accuracy of the primary diagnostic tests used in infectious diseases and international health, including microbiological, biochemical, and radiological analysis, and their conditions of use.
- Acquire competence in the field of chronic infections caused by viruses and mastery of healthcare methods and skills related to infections due to HIV and the hepatitis virus, and acquire basic skills to begin research work.
Objectives (Learning outcomes)
- HIVIAIDS INFECTION: 1) Learn about the global epidemiology of HIV infection. (2) Learn about the mechanisms of transmission of infection by HIV, the virus targets, mechanism of action of the virus, natural history of infection. (3) Meet the microbiological techniques for the diagnosis of infection, including rapid diagnostic techniques and techniques for tracking. (4) Know what options there are for the diagnosis of occult infection. (5) Meet the 3 main forms of presentation: acute infection, chronic infection and late diagnosis of infection. Introduction to the main opportunistic diseases currently grouped by CD4 count: infections associated with mild, moderate immunosuppression and severa. 6) Know the most frequent opportunistic infections grouped by syndromes and sorted by severity of immunosuppression. (a) fever and lung infiltrate: bacterial pneumonia, tuberculosis, p. jiroveci pneumonia, Cytomegalovirus, aspergillosis. (b) retinitis: Cytomegalovirus, toxoplasmosis, acute retinal necrosis. Diagnosis and treatment of each one of them. Indications of primary and secondary prophylaxis and commonly used drugs. (7) To know the main causes of space occupying cerebral lesions (toxoplasmosis, tuberculosis, primary Lymphoma of the brain), meningitis (tuberculosis, candida, Cryptococcus), fever (visceral leishmaniasis, MAC, tuberculosis infection) citopenia. (8) Know the therapeutic targets of the virus and the main drugs that act on each one of them. Learn how to create a pattern of anti-retroviral treatment. (9) Understand the objectives of treatment in chronic infection and acute infection and main indications for treatment in infected patients and prevention of infection. Meet the recommended guidelines. Criteria of primary prophylaxis of opportunistic infections and recommended guidelines. (10) Meet the families of antiretroviral toxicity medicines: toxicity associated with analog, not analogue and IPs. Learn about tenofovir / abacavir and drugs toxicity of most recent emergence of first line, such as atazanavir, darunavir and Etravirine raltegravir. (11) to know the main causes of the emergence of resistance. Learn about the concept of primary resistance and acquired resistance. Criteria for application for study of resistance. Learn about the concept of genetic barrier. Classify the family medicine antiretroviral drugs in relation to their genetic barrier and are major mutations associated with resistance to the drug. Current indications from studies of resistance.
- CHRONIC INFECTION BY VIRUSES OF THE HEPATITIS: 1) Aware of the prevalence in the world of hepatitis B and C and other viral hepatitis, mechanisms of transmission in each case and the natural history of infection not treated by virus B and C in co-infected and not coinfected with HIV. 2) Recognize the differential characteristics of the virus B and C: from the microbiological point of view, of the mechanisms of viral replication, liver cell damage, immune response of the host and mechanisms of persistence of both types of virus, mainly the virus C. 3) Know is diagnosed hepatitis B and C, the different genotypes of virus, to evaluate a patient with hepatitis B and C from the clinical point of view virologic and immunologic, and evaluation of hepatic fibrosis with invasive and non-invasive tests. (4) Meet the current criteria for the treatment of infection with the hepatitis C virus, available drugs, recommended treatment regimens in different scenarios, short- and long-term treatment effects. (5) Meet the current criteria for the treatment of infection by virus B, available drugs, recommended treatment regimens in different scenarios, short- and long-term treatment effects.
- Mandell GL. "Principles and Practice of Infectious Diseases". Churchill-Livingstone.
- Soriano V. "Manual del SIDA ". Permayer.
- Website that publishes the most prestigious clinical practice guidelines that are updated periodically by panels of experts on HIV. By registration you may receive notification by email of updates. It also offers other resources as the search in the database of drugs, both those authorized by the FDA as those who are in the phase of clinical research, clinical trials with drugs and vaccines, and warnings of the agencies on serious unexpected adverse events with the use of drugs.
- Developed and maintained by the University of California in San Francisco, offers information comprehensive update on treatment and prevention of the HIV/AIDS. Even links to drug interactions databases, guides clinical practice, alerts, collections of clinical cases and many other resources. Of great interest for the teaching is that this site offers a free HIV/AIDS treaty online updated regularly including over 100 chapters and other teaching materials written by researchers and clinicians that covers the following topics: 1) basic science 2) healthcare, 3) therapy antiretroviral, 3) clinical manifestations, 4) opportunistic infections, 5) neoplasms, 6) transmission and prevention.
- The meeting site for Spanish doctors specialists in HIV. It can be a good way of access to the documents on the HIV treatment guidelines, whether Spanish or international.
- It includes information on the situation of HIV in Spain. On all useful to consult the documents with the official recommendations on preventive and therapeutic aspects of HIV/AIDS infection.
- Website oriented to specialists in the field in the published reviews and slides over the recent studies presented in congresses and scientific meetings.
- It allows you free access to the Guidelines of the American Society of Infectious Diseases.
- Access to the European Society of AIDS Guides
Methodology and grading
- Case studies: Learning through the analysis of actual or simulated cases in order to interpret and resolve them by employing various alternative solution procedures.
- Lecture: Pass on knowledge and activate cognitive processes in students, encouraging their participation.
- Solving exercises and problems: Exercise, test, and apply previous knowledge through routine repetition.
- There will be a face to face, written, type exam test, with multiple choice (five options and only one correct answer) that will consist of 25 questions covering the specific contents of the subject.
Exercises for problem solving and participation in the Forum of the subject.
The rating system will be over 100:
- Type test exam mark: 50%
- Attendance at face-to-face activities: 20%
-Tasks/attendance in the forum of the subject: 30%