ADVANCED ORGANIC SYNTHESIS CourseCode: 3624Degree: Master's in Biotechnology and BioengineeringFaculty of Experimental SciencesYear: Year 1 of Master's in Biotechnology and BioengineeringSemester: SpringType: ElectiveLanguage: SpanishECTS credits: 3Lecture: 2Laboratory: 1Hours: 75Directed: 30Shared: 10Autonomous: 35Subject matter: Biomedical Biotechnology and BioengineeringModule: ElectiveDepartment: Course instructors are responsible for the course content descriptions in English.DescriptionAlkylation of enolates and other stabilized ions. Aldol condensation and reversible reactions. Conjugate addition of enolates. Interconversion of functional groups. Reactions of organometallic compounds. Reactions of aromatic rings. Formation of double bonds. Functionalization of alkenes. Pericyclic reactions. Reactions of oxidation and reduction of organic compounds.FacultyNameCoordinatorLectureLaboratoryFERNANDEZ LAZARO, FERNANDO■■■PAREJO PRADOS, CONCEPCION■■GUTIERREZ VILCHEZ, ANA MARIA■■ORTIZ CARRICONDO, JUAN JAVIER■■FONT SANCHIS, ENRIQUE■■MARTIN GOMIS, LUIS■■ALVAREZ SANTOS, JULIO CESAR■■SASTRE SANTOS, ANGELA■■Professional interestCompetencies and learning outcomesGeneral competenciesApply acquired knowledge to solve problems in new or unfamiliar environments within broader (or multidisciplinary) contexts related to biotechnology and bioengineering.Ability to integrate knowledge and handle the complexity of making judgments based on information that, although incomplete or limited, includes reflections on social and ethical responsibilities linked to the application of knowledge and judgments on biotechnology and bioengineering.Ability to communicate conclusions and the knowledge and latest rationale that sustain them to specialized and non-specialized audiences in a clear and unambiguous manner.Develop the capacity to continue studying in a mostly self-directed or autonomous manner.Capacity to manage and organize information.Have the ability to design and propose experiments in biotechnology and bioengineering.Be able to critically assess and discuss information.Be capable of coming up with new ideas to address problems related to biotechnology and bioengineering.Specific competenciesKnowledge and skills in the use of the most common basic and advanced experimental techniques in the field of biotechnology and bioengineering and their applications for solving specific problems in this area.Demonstrate skills to quantify phenomena and processes in biotechnology and bioengineering.Be able to critically interpret and discuss results published and/or disseminated in journals, at conferences, and in other scientific forums.Technical and scientific competence to ensure the achievement of accurate and reproducible results from which valid conclusions can be drawn in the scientific area of specialization within the field of biotechnology and bioengineering.The ability to design a research project using the scientific method, compiling and evaluating information critically to solve problems in biotechnology and bioengineering.The ability to transfer knowledge of biotechnology and bioengineering to finding effective industrial, therapeutic, or preventive interventions, preparing the application request for a patent for a biotechnological invention.Objectives (Learning outcomes)To know the main reactions that allow the formation of carbon-carbon bondsTo know the main synthetic methods for the introduction and transformation of functional groupsTo know the mechanisms of the most interesting organic reactionsTo be able to design the synthesis of a relatively complex molecule starting from reagentsContentsLecture topicsTeaching unitsFormation of carbon-carbon bondsIntroduction and transformation of functional groupsCourse contentsBasic bibliographyBorrell Bilbao, José I. Teixidó Closa, Jordi / Falcó, José Luis. "Síntesis orgánica". Madrid Síntesis 2003. Carey, Francis A. 1937-. Sundberg, Richard J. 1938-. "Advanced organic chemistry". Boston Springer 2007. Clayden, Jonathan / Greeves, Nick / Warren, Stuart / Wothers, Peter. "Organic chemistry". Oxford Oxford University Press 2001. Smith, Michael B. March, Jerry, 1929-. "March's advanced organic chemistry reactions, mechanisms, and structure". New York [etc.] John Wiley & Sons cop. 2001. Complementary bibliographyBruckner, Reinhard, 1955-. "Advanced organic chemistry [electronic resource] : reaction mechanisms /". San Diego : Harcourt/Academic Press, c2002. Fleming, Ian 1935-. "Pericyclic reactions". Oxford [etc.] Oxford University Press 2003. Jenkins, Paul R. "Organometallic reagents in synthesis". Oxford [etc.] Oxford University Press 2003. Leonard, J. Lygo, B. / Procter, G. "Advanced practical organic chemistry". Cheltenham : Stanley Thornes , cop. 1998. Saunders, John 1947-. "Top drugs : top synthetic routes / ". Oxford [etc.] Oxford University Press 2004. Schlosser, M. (Manfred). "Organometallics in synthesis [electronic resource] : third manual /". Hoboken, N.J. : Wiley, 2013. "Vogel's textbook of practical organic chemistry". New York Longman 1989. LinksSoftwareMethodology and gradingMethodologyCase studies: Learning through the analysis of actual or simulated cases in order to interpret and resolve them by employing various alternative solution procedures.Lecture: Pass on knowledge and activate cognitive processes in students, encouraging their participation.Problem-based learning: Develop active learning strategies through problem solving that promote thinking, experimentation, and decision making in the student.Solving exercises and problems: Exercise, test, and apply previous knowledge through routine repetition.GradingThe student must prepare and expose a project on a paper related to organic synthesis