Research needs an infrastructure, social support and funding. Applying the science needed transfer and protection of results. The society is sensitive to certain applications of science and rejects some practices for social and ethical reasons. International regulations are stablished on scientific basis and legal decisions regulate the scientist activity, its applicability and aspects of biosafety. The biotechnologist will deal these issues to develop their scientific and professional activity. Biotechnology offer attractive expectations accompanied by social unrest because of the uncertainty on some issues of particular concern.