UMH - CLINICAL PHARMACOLOGY

CLINICAL PHARMACOLOGY

Course

Code: 1940

Degree: Bachelor's in Medicine

Faculty of Medicine

Year: Year 3 of Bachelor's in Medicine

Semester: Fall

Type: Required

Language: Spanish

ECTS credits: 6

Lecture: 2.5

Laboratory: 3.5

Hours: 150

Directed: 60

Shared: 35

Autonomous: 55

Subject matter: Pharmacology

Module: Diagnostic and Therapeutic Procedures

Department: Pharmacology, Pediatrics and Organic Chemistry

Area: PHARMACOLOGY

Course instructors are responsible for the course content descriptions in English.

Description

Fundamental concepts and methods of rational therapeutics in a manner that they are applicable to current and future therapeutic resources in order to be able to improve care for patients via safer and more effective use of drugs.

Faculty

Name	Coordinator	Lecture	Laboratory
ZAPATER HERNANDEZ, PEDRO	■	■	■
PEIRO PEIRO, ANA MARIA		■	■
PENA PARDO, MARIA DE LOS ANGELES		■	■
HORGA DE LA PARTE, JOSÉ FRANCISCO		■	■

Professional interest

Clinical pharmacology is the subject that provides the future doctor with the skills and tools necessary to offer to their patients the best therapy available at any time

Competencies and learning outcomes

General competencies

Understand the basics of action, indications, and efficacy of therapeutic interventions based on available scientific evidence.
Establish the diagnosis, prognosis, and treatment, applying principles based on the best information available and under conditions of clinical safety.
Indicate the most appropriate therapy for the most prevalent acute and chronic processes, as well as for patients in terminal stages.
Raise and propose appropriate preventive measures for each clinical situation.
Acquire appropriate clinical experience in hospitals, clinics, and other health care institutions, under supervision, as well as basic knowledge of patient-centered health management and the appropriate use of tests, medications, and other health system resources.
Know how to use information and communication technologies in clinical, therapeutic, preventive, and research activities.

Specific competencies

Assess the risk/benefit ratio of diagnostic and therapeutic procedures.
Pharmacology of different body systems.
Know how to use drugs appropriately.

Objectives (Learning outcomes)

01Students should understand the fundamentals of action, indications and efficacy of therapeutic interventions, based on available scientific evidence
02Students should be able to establish the diagnosis and prognosis and to indicate the safest and useful treatment for a patient applying principles based on the best available information.
03Students should be able to indicate the best therapy for the most prevalent acute and chronic processes, as well as for terminally ill patients.
04Students should be able to propose appropriate preventive measures for each clinical situation.
05Students should acquire practical clinical knowledge and skills. This knowledge will be acquired under supervision in hospital, health centers and other health institutions. Also, student should acquire a basic knowledge of patient-centered cares as well as the best utilization of scientific evidence to adequate use of medicines and other resources of the health system.
06Students should learn how to use information and communication technologies in clinical, therapeutic, preventive and research activities.
07Students should learn to value the risk / benefit ratio of any diagnostic or therapeutic procedure.
08Students should be able to develop guidelines for the selection of pharmacological treatments for specific pathologies
09Students should be able to choose the best drugs for patients with specific diagnoses

Teaching units

Association between objectives and units

Objective/Unit	U1	U2
01
02
03
04
05
06
07
08
09

Schedule

Week	Directed hours	Shared hours	Autonomous hours	Total hours
1	10	5	10	25
2	10	5	10	25
3	10	5	10	25
4	10	5	10	25
5	10	5	10	25
6	10	10	5	25

Basic bibliography

P. Lorenzo; A. Moreno; I. Lizasoain; J.C. Leza; M.A. Moro; A. Portolés. "Velazquez. Farmacología Básica y Clínica". Editorial Médica Panamericana.
Harrison, Tinsley Randolph 1900- / Fauci, Anthony S. / Braunwald, Eugene / Kasper, Dennis L. "Harrison, principios de medicina interna". Madrid, México [etc.] McGraw-Hill Interamericana cop. 2012.
Baños Díez, Josep-Eladi. "Principios de farmacología clínica [bases científicas de la utilización de medicamentos]". Masson D.L.

Methodology and grading

Methodology

Case studies: Learning through the analysis of actual or simulated cases in order to interpret and resolve them by employing various alternative solution procedures.
Cooperative learning: Develop active learning through cooperative working strategies among students and promote shared responsibility to reach group goals.
Lecture: Pass on knowledge and activate cognitive processes in students, encouraging their participation.
Problem-based learning: Develop active learning strategies through problem solving that promote thinking, experimentation, and decision making in the student.
Project-based learning: Realization of a project to solve a problem, applying acquired learning and promoting abilities related to planning, design, performing activities, and reaching conclusions.
Solving exercises and problems: Exercise, test, and apply previous knowledge through routine repetition.

Grading

Theory exam will be made at the end of the teaching period. There will not be a second-chance examination on June. The theory exam will have the format of multiple-choice questions (5 answers of which only one will be valid). In the rest of exams and practices the format will be short-answers questions. The theoretical exam will evaluate the content of (see Program of the subject): [1] Capítulo 5 Harrison, “Principios de Medicina Interna”, 18ª ed., McGrawHill, 2012 (español). [2] Capítulos 61, 64, 65, 66, 67, 72, 73, 74 y 76 de Velázquez, “Farmacología Básica y Clínica”, 19ª edición, Panamericana, 2018. [3] Orden SAS 3470/2009: artículos 3, 4, 5, aptdo 2 del Art 6 y Art 7; Definición de: Estudios EPA-LA, EPA-AS, EPA-SP, EPA-OD, NO-EPA; Cuadro 1. [4] Ley 29/2006, de 26 de julio, de garantías y uso racional de los medicamentos y productos sanitarios, en su texto consolidado de 2015, en los siguientes artículos: Art 3, apartado 6; Art 7, Aptdos 1, 2 y 4; Art 8; Art 12; Art 13; Art 14, Aptdos 1 y 2; Art 15, Aptdos 2, 3 y 4; Art 19, Aptdos 1, 2, 3 y 4; Art 24, Aptdo 3; Art 46, Aptdo 1; Art 47, Aptdos 1 y 2; Art 50; Art 51; Art 53, Aptdos 1 y 2; Art 54, Aptdo 3; Art 58, Aptdos 1 y 3; Art 60; Art 62; Art 77, Aptdos 1, 3, 4 y 5; Art 82, Aptdo 1; Art 85; Art 86; Art 101. The theoretical mark will be the one reached in the theoretical exam. The mark of public expositions will be: written report mark x 0.6 + public exposition mark x 0.4 2.6. The practical mark will be obtained by adding up the qualifications of the 3 practices. Each mark will have a maximum value of 2.5 out of 10, except the clinical trials practice (practice 1), whose value is 5 out of 10. The qualifications of the practices will be done as follows: Practice 1 (clinical trials) and Practice 3 (pharmacokinetics): a) Continuous evaluation by the teacher of the student's activity (attitude, training and acquisition of skills) during the 5 days of practice b) Test performed on day 4 of practices. Practice 2 (pharmacovogilance): a) Yellow card: 30% of the qualification b) Causality algorithm: 40% of the qualification c) Evaluation of the risk/benefit ratio of the drug suspected of causing ADR including the severity of ADR: 30% of the practice score. The student who has not completed all the practices, including assistance and evaluation, will not pass the subject. The final mark of the subject will be calculated as follows: Final theoretical grade: theoretical mark x 0.3. Final practice grade: practice mark x 0.4. Exposition grade x 0.3. Grade of the subject: sum of the previous three grades. The overall grade will be established in a meeting of the teachers of the subject. The student who does not pass the subject in a first call could applies on subsequent calls only making subject parts that they have not passed (practices, exposition, theoretical examination), until the overall grade will be 5. Claims of the qualifications of the exams will be done according to the exam regulation of University Miguel Hernandez. To arrange a personal tutorial contact with the secretary of the Department of Pharmacology and Pediatrics (965919488), or with the secretary of the Clinical Pharmacology Unit of the General University Hospital of Alicante (965913868). The tutoring schedule will be from Monday to Friday from 9 to 13 AM.

Visitors: CLINICAL PHARMACOLOGY

General competencies

Specific competencies

Objectives (Learning outcomes)

Lecture topics

Teaching units

Association between objectives and units

Schedule

Course contents

Basic bibliography

Complementary bibliography

Links

Software

Methodology

Grading