This interdisciplinary laboratory is comprised of different research groups seeking to understand the fundamental mechanisms that control the first steps in correct brain development. Investigation focuses on regions throughout the embryonic brain (secondary organizers) that secrete molecules with morphogenetic capacity (FGFs, SHH, WNTs) for subsequent development of their various subdivisions (secondary prosencephalon, diencephalon, mesencephalon, and rhombencephalon). Our research extends to the understanding of the alterations of these fundamental mechanisms (genetic and molecular) that are found as small or drastic manifestations in the external and also internal morphology of the different structures the brain is made of and that are related in human beings to clinical manifestations of neurological disorders such as autism, schizophrenia, and mental retardation. Part of the tools used in this translational research is the biology of stem cells and related biotechnology in this branch of biology for the development of palliative therapies in applied medicine (clinical trials). The long-term objective of this research is to seek and test new pathways for diagnosis, prevention, and treatment of congenital brain alterations in both mental illnesses as well as neurodegenerative diseases.